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French study without a control group tested the use of colchicine in 19 patients with a first episode of acute pericarditis.
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Because most cases of acute pericarditis follow a benign course, a full diagnostic evaluation is not needed for all patients with acute pericarditis.
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Supportive treatments including administration of granulocyte colony-stimulating factor are the mainstay of treatment.
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In some subjects with mild to moderate cirrhosis, the clearance of colchicine is significantly reduced and plasma half-life prolonged compared to healthy subjects.
This condition and its complications occur more often in men, women after menopause, and people with kidney disease.
Heat modalities in the form of warm wax or paraffin baths might help, and when severe swelling is present, cold modalities may be of help.
MISSED DOSE: If you are taking colchicine regularly and miss a dose, take it as soon as you remember.
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The arterial dilatation that occurred during the use of Fab was accompanied by marked improvement in all indexes of tissue perfusion and was clearly beneficial in this patient with the adult respiratory distress syndrome and decreased cardiac output; therefore, we do not believe that any adverse effects can be ascribed to the use of the Fab fragments.
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This dose may be followed by one unit of either preparation (granule or tablet) every hour, or two units every two hours, until pain is relieved or until diarrhea ensues.
The 10-methoxy group can be replaced with halogen, alkyl, alkoxy or amino groups without affecting tubulin binding affinity, while bulky substituents reduce the activity.
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Summaries of proof: Proof tables or detailed narrative summaries of evidence, transparently describing judgements in regards to the elements in point 2 above, ought to be used as the idea for judgements concerning the high quality of evidence and the power of suggestions.
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